(Originally published July 27, 2008)
In the early nineteenth
century a French scientist named Jean Baptiste Lamarck decided that we
acquired characteristics from experiences that our parents underwent.
Russian communists applied this to agriculture but, no matter, it was a
widely discredited theory…..until recently. Now this avowed Marxist
position may have been resurrected a bit. There is a new field called
epigenetics that states pretty much what Lamarck believed. So what is
the evidence? And what exactly is it? What Lamarck said was that
individuals acquire characteristics as a result of their environment,
and now, these characteristics can be passed on to the offspring.
Much of the work in epigenetics has to do with diet; a mother’s diet
influences the offspring’s physiology. Epigenetics has to do with how
genes are regulated and influenced by the experience of the baby. I
believe it has more to do with the fetus who resides in the womb; that
his experience is influenced forevermore by the mother’s diet but also
by her moods, her anxiety and depression. Has the genetic switch been
delayed or was it premature? This can happen without making a radical
change in the gene itself but rather in how it is expressed, whether it
is shut off or on. What we are discussing is how a mother’s interaction
with her environment can pass this on to her offspring. I think we
need to understand that a fetus in the womb is always trying to adapt to
his environment and that how genes will evolve and be expressed depends
on that adaptation. For example, a mother who is anxious and who has
depleted much of her serotonin supplies cannot fulfill the young fetal
need for his own serotonin supplies. He may well grow up deficient in
inhibitory or repressive capacity and be an anxiety case forevermore;
this evolves into attention deficit in his youth and his continued
inability to have a cohesive cognitive ability. I think it is extremely
important that all this occurs while the fetal brain is rapidly
developing and needs proper input to evolve normally. An anxious mother
is so agitated that the neuronal input into the baby she is carrying is
so extreme that he cannot adapt and integrate this input. Thereafter,
this is the kind of person who cannot accept too much stimulation
because the internal input is so great that anything from the outside,
just two terms papers, can be overwhelming.
I have discussed
the work of Michael Meaney of McGill University who has worked with
mice and found that very early neglect by the mother results in lifelong
alterations. In thirteen men who had committed suicide, all of whom
suffered from child abuse, there were epigenetic effects. Abuse has
many forms but to me those most deleterious is the abuse of a mother who
smokes, drinks or takes drugs during pregnancy. Abuse means adversely
affect a child’s development. Meaney found the same changes in thirty
five people who suffered from schizophrenia. Here, several of the genes
involved with the unfurling of key neurotransmitters (which ordinarily
help to repress pain or noxious stimuli) where affected. New work has
related epigenetics to the occurrence of cancer. What has been called
the effects on epigenetic settings I call changing the set-points of
many biologic states; this includes the set-points of the
neurotransmitters that w
Ill later make us chronically comfortable or
uncomfortable. Not feeling good in our skin is one way to state it.
What is very new is that experiences of the mother affects the sperm of
the offspring, and that may affect how the grandchildren develop. It
may be that smoking or drug taking in while the embryo is just forming
can later affect sperm production. The meaning of all this is that what
happens in the womb while the organism is getting organized can affect
the baby for a lifetime. It is so important that we not neglect this
period when we attempt to understand and treat those with emotional
problems. The more remote the imprint the more widespread the later
effects, in my opinion. When a carrying mother is under stress her
stress hormone level is high. When the levels remain high for a long
time the immune system is compromised, and that might well affect the
immune status of the offspring. And as I note elsewhere, a strong
immune system (natural killer cells) is needed to stay on the lookout
for newly developing cancer cells. It is not that a deficient immune
system can lead to cancer, it is that a weak maternal immune system does
not impart a strong immune capability to the baby; and the same
dislocated physiology of the mother can also affect the fetus, setting
the stage for later catastrophic disease. Womb-life has largely been
neglected in the psychological literature. It is time to reorient
ourselves.
SMALL FEET AND SMALL BREASTS: CANCER?
Are
small feet and small breasts desirable? Is it good or bad? It’s more
serious than that. It is neither good nor bad but whether that size has
arrived at its genetic destination. That is, due to heredity has the
size fulfilled the genetic intention? If not, there can be serious
repercussions. What it means to me, and now we leave the arena of
strict science, is that repression has interceded to slow down or
inhibit growth. How do I know? Some of my patients have reported foot
growth, chest growth, breast growth and other kinds of growth after
about a year of therapy. (We have a letter of a former patient who
reported foot growth of several sizes after therapy). All that has
happened in my therapy is lifting repression and liberating pain. If we
reason backward we might say that repression prohibited proper growth
from taking place. That means to me constant pressure in key sites
against growth; against genetic destinations. And that again can mean
the possibility of serious illness, possibly cancer. Pressure on the
cells to stop this unfolding can be enormous. Until one has seen the
liberation of pain it is difficult to comprehend.
So we can
only say that one’s breasts are too small when we see if they grow as a
result of this liberation. And I believe that will only happen when
the patient arrives at deeply implanted pain, at birth and before, when
so many hormones are affected; where so many set-points are dislocated
and fixed. I think that, in this sense, the therapy may have an
anti-cancer effect. Can you imagine the pressure our biology exerts to
fulfill its genetic promise? That pressure continues against a constant
pressure to hold it back. The result too often can be disease as the
cells become deformed and dislocated. It is not only the obvious
breasts and feet, which are, after all, measurable, but there my be so
effects we cannot measure; for example, the kidneys, heart or liver. We
see that wherever we have looked, (serotonin/impramine: natural killer
cells) there are significant changes. We would expect the same with key
organ systems. In other words, pain and repression are laid down as
total experience, which means that just about every system is involved
in the imprint of the memory. So we would expect that all key organ
systems would be affected. That remains to be studied. But we would
also expect that those systems, which are inherently weak and
vulnerable, would be seriously affected by that repression. The
answer? Have a good gestation and birth and infancy. Failing that,
relive the key pains set down and undo the massive repression.
There are effects we cannot measure; for example, the kidneys, heart
or liver. We see that wherever we have looked, (serotonin/impramine:
natural killer cells) there are significant changes. We would expect
the same with key organ systems. In other words, pain and repression are laid down as
total experience, which means that just about every system is involved
in the imprint of the memory. So we would expect that all key organ
systems would be affected. That remains to be studied. But we would
also expect that those systems, which are inherently weak and
vulnerable, would be seriously affected by that repression. The
answer? Have a good gestation and birth and infancy. Failing that,
relive the key pains set down and undo the massive repression.
In
writing about the imprint, I will note again that one way we know that
very early imprinted pain endures is that many entering patients have
high stress hormone levels which normalize after one year of the
therapy. What this may mean is that the imprint endures, is a constant
danger, and must be fought against. That danger is signaled by the high
cortisol (stress hormone) levels. Why is it, then, that the levels
come down to normal after a time? Because the imprint is no longer a
force; It is now simply a memory. The force of the pain has been felt
and integrated. It is not as though there is a reliving of the memory
and then we find changes in the imprint; it is that the way the memory
is held and engraved is through these various changes such as in stress
hormone levels. The danger is no longer in evidence; the system can
relax. The battle is over. As all systems normalize it means that there
is no longer an irrevocable memory to deal with. The imprint as a total
physiologic event no longer exists. Can we become neurotic again? Not
in the same way because the harmful memory is gone. What we often
cannot change are the secondary changes already in evidence due to the
damage inflicted beforehand.